# TCI Simulator Notices

Copyright (C) 2026 TCI Simulator contributors.

TCI Simulator is free software distributed under the GNU General Public
License version 3.0 only. There is no warranty, including any implied warranty
of merchantability or fitness for a particular purpose. See `LICENSE`.

## SimTIVA

The target-planning behavior in `js/simtiva.js`, related compatibility
parameters, and compatibility tests were adapted and modified in 2026 from,
or developed to interoperate with, the SimTIVA project:

- Project: SimTIVA
- Author/creator: Terence Luk
- Source: https://github.com/luktinghin/simtiva
- License: GNU General Public License v3.0

This project is an independent modified work. It is not an official SimTIVA
release and is not endorsed by Terence Luk.

## Open TCI And STANPUMP

The compartment-model mathematics and target-control approach acknowledge:

- Open TCI Initiative: https://opentci.org/code
- STANPUMP by Steven L. Shafer, M.D.:
  https://opentci.org/code/stanpump

Open TCI states that its pharmacokinetic mathematics is based on published
articles and textbooks describing mammillary compartment models. This project
does not claim endorsement by Open TCI or the STANPUMP author.

## Published Pharmacokinetic Models

The implementation names and cites the Marsh, Schnider, Eleveld, and Minto
population pharmacokinetic models in `js/models.js`. Model names and published
equations do not imply certification, validation, or endorsement of this
implementation by the original researchers.

## Modifications

TCI Simulator includes a newly designed mobile interface, charting,
simulation controls, forecast visualization, localization, and additional
simulation behavior. It is not a verbatim or official distribution of
SimTIVA.